Former Trump security advisor sees no off-ramp this time around for Iran, Israel and America

Trump seems to have no appetite for a deal now – he just wants Iran’s regime gone.

After U.S. and Israeli missiles struck Iran’s nuclear sites in June 2025, Tehran responded with a limited attack on the American airbase in Qatar. Five years before that, a U.S. drone strike against Qasem Soleimani, head of the powerful Islamic Revolutionary Guard Corps Quds Force, was followed by an attack on two American bases in Iraq shortly thereafter.

Expect none of that restraint by Iran’s leaders following the latest U.S. and Israeli military operation currently playing out in the Gulf nation.

In the early hours of Feb. 28, 2026, hundreds of missiles struck multiple sites in Iran, including a compound housing Supreme Leader Ayatollah Ali Khamenei, who Iranian state media later confirmed had died in the attack.

“Operation Epic Fury,” as the U.S. Department of Defense has called the strikes, follows months of U.S. military buildup in the region. But it also come after apparent diplomatic efforts, in the shape of a series of nuclear talks in Oman and Geneva aimed at a peaceful resolution.

Any such deal is surely now completely off the table. In scale and scope, the U.S. and Israel attack goes far beyond any previous strikes on the Gulf nation.

In response, Iran has said it will use “crushing” force. As an expert on Middle East affairs and a former senior official at the National Security Council during the first Trump administration, I believe the calculus both in Washington and more so in Tehran is very different from earlier confrontations: Iran’s leaders almost certainly see this as an existential threat given President Donald Trump’s statement and the military campaign already underway. And there appears to be no obvious off-ramp to avoid further escalation.

What we should expect now is a response from Tehran that utilizes all of its capabilities – even though they have been significantly degraded. And that should be a worry for all nations in the region and beyond.

The apparent aims of the US operation

It is important to note that we are in the early stages of this conflict – much is unknown.

As of Feb. 28, it is unclear who has been killed among Iran’s leadership and to what extent Iran’s ballistic missile capabilities have been degraded. The fact that ballistic missiles have been launched at regional states that host U.S. military bases suggests that, at a minimum, Iran’s military capabilities have not been entirely wiped out.

Iran fired over 600 missiles against Israel last June during their 12-day war, but media reporting and Iranian statements over the past month suggested that Iran managed to replenish some of its missile inventory, which it is now using.

Clearly Washington is intent on crippling Iran’s ballistic program, as it is that capability that allows Iran to threaten the region most directly. A sticking point in the negotiations in Geneva and Oman was U.S. officials’ insistence that both Iran’s ballistic missiles and its funneling of support to proxy groups in the region be on the table, along with the longstanding condition that Tehran ends all uranium enrichment. Tehran has long resisted attempts to have limits on its ballistic missiles as part of any negotiated nuclear deal given their importance in Iran’s national security doctrine.

This explains why some U.S. and Israeli strikes appear to be aimed at taking out Iran’s ballistic and cruise missile launch sites and production facilities and storage locations for such weapons.

With no nuclear weapon, Iran’s ballistic missiles have been the country’s go-to method for responding to any threat. And so far in the current conflict, they have been used on nations including the United Arab Emirates, Qatar, Kuwait and Bahrain.

‘It will be yours to take’

But the Trump administration appears to have expanded its aims beyond removing Iran’s nuclear and non-nuclear military threat. The latest strikes have gone after leadership, too, taking out Khamenei alongside other key members of the regime.

It is clear that the U.S. administration hopes that regime change will follow Operation Epic Fury. “When we are finished, take over your government. It will be yours to take,” Trump told Iranians via a video message recorded during the early hours of the attack.

[A man in a suit and a baseball cap with USA on it stands at a podium.]

*U.S. President Donald Trump addressed the nation on Iran strikes. US President Trump Via Truth Social/Anadolu via Getty Images*

Regime change carries risks for Trump

Signaling a regime change operation may encourage Iranians unhappy with decades of repressive rule and economic woes to continue where they left off in January – when hundreds of thousands took to the street to protest.

But it carries risks for the U.S. and its interests. Iran’s leaders will no longer feel constrained, as they did after the Soleimani assassination and the June 2025 conflict. On those occasions, Iran responded in a way that was not even proportionate to its losses – limited strikes on American military bases in the region.

Now the gloves are off, and each side will be trying to land a knockout blow. But what does that constitute? The U.S. administration appears to be set on regime change. Iran’s leadership will be looking for something that goes beyond its previous retaliatory strikes – and that likely means American deaths. That eventuality has been anticipated by Trump, who warned that there might be American casualties.

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